55832-80-9

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-5-(phenylthio)-
• CAS NO: 55832-80-9
• Molecular Formula: C12H12N2O2S
• Molecular Weight: 248.305
• Mol File: 55832-80-9.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-5-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-5-(phenylthio)-(55832-80-9)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-5-(phenylthio)-(55832-80-9)

Safety Data

• Hazardous Substances Data: 55832-80-9(Hazardous Substances Data)

Upstream product

• 40738-83-8 5-iodo-1,3-dimethyluracil 
• 874-14-6 1,3-dimethyluracil 
• 882-33-7 diphenyldisulfane 
• 7033-39-8 5-bromo-1,3-dimethyluracil 
• 930-69-8 sodium thiophenolate 
• 13133-62-5 thiophenolate 
• 49846-86-8 6-cyano-1,3-dimethyluracil 
• 108-98-5 thiophenol 
• 931-59-9 benzenesulfenyl chloride 

Downstream Products

• 247220-10-6 5-benzenesulfinyl-1,3-dimethyluracil 
• 13509-52-9 1,3,6-trimethyluracil 
• 874-14-6 1,3-dimethyluracil 

Relevant articles and documents

Iodine/persulfate-promoted site-selective direct thiolation of quinolones and uracils

A simple and general method for direct thiolation of 4-quinolones with disulfides or thiols under I2/K2S2O8 system has been developed. Under the optimal conditions, the C–S bond coupling can take place effectively with good to decent yields and excellent regioselectivity of the S-linked products. The established metal-free site-selective approach was also applicable to transform a range of uracil substrates to the thio-substituted products under mild conditions. Further transformation to the sulfone derivatives can be conveniently performed in one-pot. These easy-to-handle protocols represent a useful and interesting synthetic alternative with good substrate scope and functional group compatibility.

Cu(ii)-catalyzed sulfide construction: both aryl groups utilization of intermolecular and intramolecular diaryliodonium salt

A sulfur-iodine exchange protocol of diaryliodonium salts with inorganic sulfur salt was developed. Both aryl groups in the diaryliodonium salt were fully exerted in this transformation. Five- to eight-membered sulfur-containing heterocycles were achieved. Note that [1]benzothieno-[3,2-b][1]benzothiophene (BTBT) (an organic field-effect transistor (OFET) material) and Zaltoprofen were efficiently established through this method.

Palladium-catalyzed carbon-sulfur cross-coupling reactions with indium tri(organothiolate) and its application to sequential one-pot processes

(Chemical Equation Presented) It was found that indium tri(organothiolate) is an effective nucleophilic coupling partner in Pd-catalyzed C-S cross-coupling reactions to produce the functionalized sulfides in excellent yields with high atom efficiency and