558466-17-4Relevant academic research and scientific papers
A Library of Fluorinated Electrophiles for Chemical Tagging and Materials Synthesis
Kasper, Jonathan J.,Hitro, Jamie E.,Fitzgerald, Sabrina R.,Schnitter, Joseph M.,Rutowski, James J.,Heck, John A.,Steinbacher, Jeremy L.
, p. 8095 - 8103 (2016)
Various applications could benefit from new fluorinated molecules that offer chemical handles for quickly functionalizing reactive surfaces and molecules. Herein, we report the synthesis of a library of fluorinated molecules that contain nonafluoro-tert-butyl groups and electrophilic handles, mostly acrylates and acrylamides. Featuring a variety of hydrophobic and hydrophilic linkers, these molecules could find use in polymer chemistry, biomaterials, biomedical imaging, and protein tagging.
BETA-AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS
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Page 176, (2010/02/08)
Provided are novel compounds having an inhibitory activity against production or secretion of β-amyloid protein. They embrace compounds represented by the following formula (1): and capable of being replaced with a variety of substituents; and salts thereof, and solvates of any one of them.
