558473-96-4Relevant articles and documents
Facile routes to alkoxymaleimides/maleic anhydrides
Sahoo, Manoj Kumar,Mhaske, Santosh B.,Argade, Narshinha P.
, p. 346 - 349 (2003)
New routes to alkoxymaleic anhydrides 1a/b have been described in good yields via base-induced chemoselective vinylic substitution of bromo atom in bromomaleimide 4 with alkanols, and base-induced oxa-Micahel addition of alkanols to dialkyl acetylene-dicarboxylates 8a/b as key steps. An unusual acyl exchange in the conversion of 6a/b to 1a/b under very simple and mild reaction conditions is noteworthy.
Ring Substituent Effects on the Thiol Addition and Hydrolysis Reactions of N-Arylmaleimides
Chen, Yingche,Tsao, Kelvin,De Francesco, élise,Keillor, Jeffrey W.
, p. 12182 - 12192 (2016/01/09)
Maleimide groups are used extensively in bioconjugation reactions, but limited kinetic information is available regarding their thiol addition and hydrolysis reactions. We prepared a series of fluorogenic coumarin maleimide derivatives that differ by the
