5585-14-8

Basic information

• Product Name: 3,4-DIPHENYLFURAZAN2-OXIDE
• Synonyms: 3,4-DIPHENYLFURAZAN2-OXIDE;3,4-diphenyl-1,2,5-oxadiazole-2-oxide;Diphenylfuroxan
• CAS NO: 5585-14-8
• Molecular Formula: C₁₄H₁₀N₂O₂
• Molecular Weight: 238.2414
• Mol File: 5585-14-8.mol
• Article Data: 59

Chemical Properties

• Boiling Point: 376.2°C at 760 mmHg
• Flash Point: 181.3°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 1.6E-05mmHg at 25°C
• Refractive Index: 1.635
• CAS DataBase Reference: 3,4-DIPHENYLFURAZAN2-OXIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIPHENYLFURAZAN2-OXIDE(5585-14-8)
• EPA Substance Registry System: 3,4-DIPHENYLFURAZAN2-OXIDE(5585-14-8)

Safety Data

• Hazardous Substances Data: 5585-14-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 5688, 1955 DOI: 10.1021/ja01626a066

InChI:InChI=1/C14H10N2O2/c17-16-14(12-9-5-2-6-10-12)13(15-18-16)11-7-3-1-4-8-11/h1-10H

Upstream product

• 572-43-0 1,2-Diphenyl-ethane-1,2-dione dioxime 
• 56-23-5 tetrachloromethane 
• 873-67-6 benzonitrile oxide 
• 2548-47-2 2,3-diphenyl-1,3-butadiene 
• 529-19-1 2-Methylbenzonitrile 
• 766-84-7 3-chloro-benzonitrile 
• 1527-89-5 3-methoxybenzonitrile 
• 13049-41-7 1,1-dimethoxy-2-phenylethene 
• 28525-13-5 4-(phenylsulfonyl)benzonitrile 
• 103-26-4 Methyl cinnamate 
• 100-47-0 benzonitrile 
• 612-24-8 o-nitrobenzonitrile 
• 13591-25-8 dibenzylidene-diazoxane-N-oxide 
• 572-45-2 benzil dioxime 

Downstream Products

• 65-85-0 benzoic acid 
• 572-43-0 1,2-Diphenyl-ethane-1,2-dione dioxime 
• 19768-02-6 3,4-diphenylfurazan 
• 103-71-9 phenyl isocyanate 
• 60148-18-7 5-dodecyl-3-phenyl-4,5-dihydro-isoxazole 
• 5796-07-6 phenyl-carbamic acid dodecyl ester 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 57065-93-7 (4RS,5RS)-3-phenyl-4,5-dihydro-isoxazole-4,5-dicarboxylic acid diethyl ester 
• 102-08-9 N,N-diphenylthiourea 
• 103-72-0 phenyl isothiocyanate 
• 68-12-2 N,N-dimethyl-formamide 
• 1017-09-0 5-n-butyl-3-phenyl-Δ²-isoxazoline 
• 82164-06-5 3-Phenyl-isoxazole-4,5-dicarboxylic acid bis-benzylamide 
• 100-47-0 benzonitrile 

Relevant articles and documents

Stereoselective cycloaddition of nitrile oxides to a dispiroketal-protected but-3-ene-1,2-diol

The influence of a dispiroketal protecting group on the π-facial selectivity of nitrile oxide cycloaddition of S-but-3-ene-1,2-diol has been investigated. Ethoxycarbonylformonitrile oxide and benzonitrile oxide undergo regiospecific and diasteroeselective addition to alkene 7 to afford isoxazolines 11 and 12. The major adducts (11a and 11b) are formed with 44% and 50% d.e. respectively, and in each case have S-configuration at C-5, the new stereogenic centre.

Synthesis of Biologically Active Heterospirocycles through Iterative 1,3-Dipolar Cycloaddition Pathways

We demonstrate the novel spiroannulation of exo-imines with 1,3-dipoles, for the first time, leading to 3D spirocycles with a secondary amine (NH) in the spiro-ring. The synthetic method described herein allows access to these previously unexplored heterospirocyclic cores that have application in the discovery of functional molecules for medicinal and materials science. This was demonstrated by discovering an unprecedented class of heterospirocycles with antimalarial activity against the human protozoan P. falciparum.

Synthesis method of furoxan compound

The invention discloses a synthesis method of a furazan oxide compound. The synthesis method comprises the following step of: oxidizing a glyoxime compound by taking iodobenzene diethyl ester as an oxidizing agent to carry out a reaction to obtain the fur

Heterocyclization of 5-(Arylmethylidene)pyrimidine-2,4,6(1H,3H,5H)-triones with Arenecarbaldehyde Oximes in the Presence of N-Bromosuccinimide and Triethylamine

5-(Arylmethylidene)pyrimidine-2,4,6(1H,3H,5H)-triones reacted with substituted benzaldehyde oximes in the presence of N-bromosuccinimide and triethylamine to give 1,4-diaryl-2-oxa-3,7,9-triazaspiro-[4.5]dec-3-ene-6,8,10-triones and 3,4-diaryl-1,2,5-oxadia