55888-93-2Relevant academic research and scientific papers
The birch reduction of heterocyclic compounds V birch reduction of 2- and 5-acylfuran-3-carboxylic acids and reductive elimination of 2-(arylmethoxymethyl)furan-3-carboxylic acids
Ohta,Doe,Morimoto,Kinoshita
, p. 751 - 755 (2007/10/03)
The Birch reduction of 2- and 5-acylfuran-3-carboxylic acid 1 and 4 gave 2-acyl-2,3-dihydrofuran-3-carboxylic acid 2 and 5-acyltetrahydrofuran-3-carboxylic acid 5, respectively. Further examination of the reductive elimination was also studied on 2-(arylm
Synthesis of cytotoxic furonaphthoquinones: Regiospecific synthesis of diodantunezone and 2-ethylfuronaphthoquinones
Perry, Philip J.,Pavlidis, Vasilios H.,Hadfield, John A.
, p. 3195 - 3204 (2007/10/03)
Diodantunezone was first isolated from Lantana achyrantifolia (Verbenaceae) and originally assigned as 8-hydroxy-4,9-dihydronaphtho[2,3-b]furan-4,9-dione 1a but its structure was later revised to 5-hydroxy-4,9 dihydronaphtho[2,3-b]furan-4,9-dione 2a. The regiospecific synthesis of diodantunezone 2a and its methyl ether, 5-methoxy-4,9-dihydronaphtho[2,3-b]furan-4,9-dione 2b, is described. The preparation of two 2-ethylfuronaphthoquinones 14a and 14b is also described. All four quinones were shown to possess cytotoxic activity against three cell lines (1.3-17.4 μmol dm-3).
The rapid reduction of α,α-diaryl alcohols to the corresponding alkanes using iodotrimethylsilane
Perry, Philip J.,Pavlidis, Vasilios H.,Coutts, Ian G. C.
, p. 101 - 111 (2007/10/03)
The utility of iodotrimethylsilane has been extended to include the rapid and highly selective reduction of α,α-diaryl alcohols. The reduction of a series of α-hydroxyfuroic acids in near quantitative yield has been demonstrated and the mechanism discussed.
