55913-06-9

Basic information

• Product Name: 3'-methoxybenzoin
• Synonyms: 3'-methoxybenzoin
• CAS NO: 55913-06-9
• Molecular Weight: 242.274
• Mol File: 55913-06-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3'-methoxybenzoin(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-methoxybenzoin(55913-06-9)
• EPA Substance Registry System: 3'-methoxybenzoin(55913-06-9)

Safety Data

• Hazardous Substances Data: 55913-06-9(Hazardous Substances Data)

Upstream product

• 1580052-46-5 C₁₈H₂₀O₂S₂ 
• 54308-43-9 2-(3-methoxyphenyl)-1,3-dithiane 
• 591-31-1 3-methoxy-benzaldehyde 
• 100-52-7 benzaldehyde 

Downstream Products

• 40103-80-8 1-(3-methoxyphenyl)-2-phenylethane-1,2-dione 

Relevant articles and documents

Asymmetric transfer hydrogenation of unsymmetrical benzils

In this paper, the asymmetric transfer hydrogenation of unsymmetrical benzils with m, p-substituents was conducted with a substrate/catalyst molar ratio of 100 at 40°C for 24 h to produce (S,S)-hydrobenzoins in good yields (76.2% to 97.1%) with high diastereomeric (syn/anti = 10.8 to 29.7/1) and enantiomeric purities (86.1%ee syn to 98.9%ee syn). Unfortunately, the unsymmetrical benzils with the o-substituents such as electron-donating (R = CH3, OCH3) and electron-withdrawing groups (R = F, Cl, CF3) resulted in poor yields (0% to 31.2%), even at 40°C for 72 h. These products had inefficient diastereoselectivities (syn/anti = 1.5 to 5.0/1) caused by steric effects. Furthermore, the results of a dynamic-kinetic study were used to propose a plausible reaction pathway of unsymmetrical benzil using 3-methoxy-1,2-diphenyl ethanedione as an example.