55981-16-3

Basic information

• Product Name: 2-acetoxy-5-chloro-N-(5-nitro-thiazol-2-yl)-benzamide
• CAS NO: 55981-16-3
• Molecular Weight: 341.732
• Mol File: 55981-16-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-acetoxy-5-chloro-N-(5-nitro-thiazol-2-yl)-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-acetoxy-5-chloro-N-(5-nitro-thiazol-2-yl)-benzamide(55981-16-3)
• EPA Substance Registry System: 2-acetoxy-5-chloro-N-(5-nitro-thiazol-2-yl)-benzamide(55981-16-3)

Safety Data

• Hazardous Substances Data: 55981-16-3(Hazardous Substances Data)

Upstream product

• 321-14-2 5-chloro-2-hydroxybenzoic acid 
• 5538-53-4 2-acetoxy-5-chlorobenzoyl chloride 
• 121-66-4 2-amino-5-nitro-1,3-thiazole 

Relevant articles and documents

Development of 5-nitrothiazole derivatives: Identification of leads against both replicative and latent Mycobacterium tuberculosis

Twenty eight 5-nitrothiazole derivatives were synthesized and evaluated for in vitro activities against Mycobacterium tuberculosis (MTB), cytotoxicity against HEK 293T. Among the compounds, 5-nitro-N-(5-nitrothiazol-2-yl)furan-2- carboxamide (20) was found to be the most active compound in vitro with MICs of 5.48 μM against log-phase culture of MTB and also non-toxic up to 100 μM.