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[(2-amino-5H-purin-6-yl)sulfanyl]acetic acid, also known as 6-Thioguanine, is a chemical compound that features a purine base akin to adenine and guanine, with a sulfhydryl group connected to an acetic acid molecule. It is recognized for its medicinal properties, particularly in the treatment of specific leukemia types and autoimmune diseases.

5599-15-5

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5599-15-5 Usage

Uses

Used in Pharmaceutical Industry:
[(2-amino-5H-purin-6-yl)sulfanyl]acetic acid is used as an antineoplastic agent for the treatment of certain leukemia types. It functions by disrupting the growth and proliferation of cancer cells, thereby inhibiting their spread.
Additionally, in the field of autoimmune diseases:
[(2-amino-5H-purin-6-yl)sulfanyl]acetic acid is used as an immunosuppressive agent to suppress the immune system and manage autoimmune disorders. It achieves this by mimicking and substituting for the natural purines found in DNA and RNA, thus affecting cellular processes.

Check Digit Verification of cas no

The CAS Registry Mumber 5599-15-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,9 and 9 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5599-15:
(6*5)+(5*5)+(4*9)+(3*9)+(2*1)+(1*5)=125
125 % 10 = 5
So 5599-15-5 is a valid CAS Registry Number.

5599-15-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Amino-6-carboxymethylthiopurin

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5599-15-5 SDS

5599-15-5Downstream Products

5599-15-5Relevant academic research and scientific papers

In search of a new prototype in CK2 inhibitors design

Maslyk, MacIej,Zapico, Jose M.,Swider, Robert,Martin-Santamaria, Sonsoles,Ramos, Ana,De Pascual-Teresa, Beatriz

, p. 54 - 71 (2011/06/18)

A series of purines have been synthesized and the compounds have been tested for their inhibitory activity against CK2. Some of them have shown an interesting activity, demonstrating that this purine-based scaffold can be considered as a new starting poin

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