56007-76-2Relevant academic research and scientific papers
Photogeneration of Highly Electrophilic Benzoylketene from Dibenzoyldiazomethane in Aqueous Solvents: Reaction with Amino Acids and DNA Cleavage
Nakatani, Kazuhiko,Shirai, Junya,Tamaki, Ryo,Saito, Isao
, p. 5363 - 5366 (2007/10/02)
Photoirradiation of dibenzoyldiazomethane in the presence of amino acid derivatives in aqueous solutions efficiently produced the addition products through a reaction with photogenerated benzoylketene.Efficient DNA cleavage was observed with a dibenzoyldiazomethane derivative, possessing a cationic side chain under photoirradiation conditions.
Stable Enols of α-dibenzoylmethanes
Regitz, Manfred,Schaefer, Ansgar
, p. 1172 - 1185 (2007/10/02)
The enols 13a-m of α-(aryloxy)- and α-(alkyloxy)dibenzoylmethanes 4a-m are obtained by decomposition of the copper chelates 11a-m with sulfuric acid.The copper compounds are synthesized either by ester condensation of the acetophenones 6h-m with phenyl benzoate (7) or by nucleophilic substitution of α-bromodibenzoylmethane (9) with the phenols 10a-g.The enolates 8, primarily formed in the presence of sodium hydride or triethylamine, respectively, are directly converted into the chelates 11 with copper(II) acetate.The enols 13 are characterized by isomerization to the β-diketones 4 as well as by bromination to 12.
