56014-42-7

Upstream product

• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 105-36-2 ethyl bromoacetate 
• 64-17-5 ethanol 
• 108515-17-9 N-(3,4-dimethoxy-phenethyl)-glycine nitrile 

Downstream Products

• 102706-93-4 N-(3-ethoxycarbonyl-butyryl)-N-(3,4-dimethoxy-phenethyl)-glycine ethyl ester 
• 1166834-68-9 ethyl N-(4,5-dimethoxyphenethyl)-3,4-bis-(3,4-dimethoxyphenyl)pyrrole-2-carboxylate 
• 1166834-65-6 N-(2-(2-bromo-4,5-dimethoxyphenyl)ethyl)glycine ethyl ester 
• 56014-50-7 N-(3,4-dimethoxy-phenethyl)-N-(toluene-4-sulfonyl)-glycine 
• 131506-11-1 4-(4-Chloro-benzenesulfonylaminocarbonyl)-N-((S)-1-{[2-(3,4-dimethoxy-phenyl)-ethyl]-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-carbamoyl}-2-methyl-propyl)-benzamide 
• 137302-22-8 ((S)-1-{[2-(3,4-Dimethoxy-phenyl)-ethyl]-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-carbamoyl}-2-methyl-propyl)-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Domino Bischler–Napieralski – Michael Reaction and Oxidation – New Route to Coumarin-Pyrrole-Isoquinoline Fused Pentacycles

Lamellarin scaffold is synthesized by a metal free convergent route involving domino Bischler–Napieralski reaction – Michael reaction – oxidation sequence. Six lamellarin analogues were synthesised having substituent on aryl as well as coumarin ring A.

The application of vinylogous iminium salt derivatives to efficient formal syntheses of the marine alkaloids lamellarin G trimethyl ether and ningalin B

Studies directed at the synthesis of lamellarin G trimethyl ether and ningalin B via vinylogous iminium salt derivatives are described. The successful strategy relies on the formation of a 2,4-disubstituted pyrrole or a 1,2,3,4-tetrasubstituted pyrrole fr