5602-32-4Relevant academic research and scientific papers
One-pot mechanosynthesis of aromatic amides and dipeptides from carboxylic acids and amines
?trukil, Vjekoslav,Bartolec, Boris,Portada, Tomislav,Dilovi?, Ivica,Halasz, Ivan,Margeti?, Davor
supporting information, p. 12100 - 12102 (2013/01/16)
Environmentally friendly one-pot synthesis of amides, bis-amides and dipeptides by mechanochemical carbodiimide-mediated coupling of carboxylic acids and amines is described; high reaction yields and simple aqueous work-up allow for the clean, practical and fast preparation of a variety of compounds containing the amide bond from readily accessible reagents.
