56046-15-2 Usage
Description
[S,(-)]-7-Hydroxy-3,7-dimethyloctanoic acid, with the molecular formula C10H20O3, is a chiral compound that possesses a non-superimposable mirror image. The S-enantiomer is the active form, and it is commonly found in nature as a key component of pheromones in various insect species. [S,(-)]-7-Hydroxy-3,7-dimethyloctanoic acid also holds promise for pharmaceutical applications, particularly in the development of anti-inflammatory drugs, and serves as a precursor for synthesizing a range of organic compounds. Its anti-inflammatory and antioxidant properties suggest potential utility in diverse medical applications.
Uses
Used in Pharmaceutical Applications:
[S,(-)]-7-Hydroxy-3,7-dimethyloctanoic acid is used as an active pharmaceutical ingredient for its anti-inflammatory properties, which can be beneficial in the treatment of various conditions characterized by inflammation.
Used in Insect Pheromone Production:
In the field of entomology, [S,(-)]-7-Hydroxy-3,7-dimethyloctanoic acid is used as a key component in the synthesis of pheromones for several insect species, playing a crucial role in mating and communication behaviors.
Used in Organic Synthesis:
[S,(-)]-7-Hydroxy-3,7-dimethyloctanoic acid is utilized as a precursor in the synthesis of various organic compounds, contributing to the development of new chemical entities for different applications, including pharmaceuticals, agrochemicals, and materials science.
Used in Antioxidant Formulations:
Due to its antioxidant properties, [S,(-)]-7-Hydroxy-3,7-dimethyloctanoic acid can be used as an additive in the formulation of products that require protection against oxidative damage, such as in the food and cosmetic industries.
Check Digit Verification of cas no
The CAS Registry Mumber 56046-15-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,0,4 and 6 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 56046-15:
(7*5)+(6*6)+(5*0)+(4*4)+(3*6)+(2*1)+(1*5)=112
112 % 10 = 2
So 56046-15-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H20O3/c1-8(7-9(11)12)5-4-6-10(2,3)13/h8,13H,4-7H2,1-3H3,(H,11,12)
56046-15-2Relevant articles and documents
The Odorant (R)-Citronellal Attenuates Caffeine Bitterness by Inhibiting the Bitter Receptors TAS2R43 and TAS2R46
Suess, Barbara,Brockhoff, Anne,Meyerhof, Wolfgang,Hofmann, Thomas
, p. 2301 - 2311 (2018/03/21)
Sensory studies showed the volatile fraction of lemon grass and its main constituent, the odor-active citronellal, to significantly decrease the perceived bitterness of a black tea infusion as well as caffeine solutions. Seven citronellal-related derivatives were synthesized and shown to inhibit the perceived bitterness of caffeine in a structure-dependent manner. The aldehyde function at carbon 1, the (R)-configuration of the methyl-branched carbon 3, and a hydrophobic carbon chain were found to favor the bitter inhibitory activity of citronellal; for example, even low concentrations of 25 ppm were observed to reduce bitterness perception of caffeine solution (6 mmol/L) by 32%, whereas (R)-citronellic acid (100 pm) showed a reduction of only 21% and (R)-citronellol (100 pm) was completely inactive. Cell-based functional experiments, conducted with the human bitter taste receptors TAS2R7, TAS2R10, TAS2R14, TAS2R43, and TAS2R46 reported to be sensitive to caffeine, revealed (R)-citronellal to completely block caffeine-induced calcium signals in TAS2R43-expressing cells, and, to a lesser extent, in TAS2R46-expressing cells. Stimulation of TAS2R43-expressing cells with structurally different bitter agonists identified (R)-citronellal as a general allosteric inhibitor of TAS2R43. Further structure/activity studies indicated 3-methyl-branched aliphatic aldehydes with a carbon chain of ≥4 C atoms as best TAS2R43 antagonists. Whereas odor-taste interactions have been mainly interpreted in the literature to be caused by a central neuronal integration of odors and tastes, rather than by peripheral events at the level of reception, the findings of this study open up a new dimension regarding the interaction of the two chemical senses.
