56107-98-3Relevant academic research and scientific papers
Iridium-catalyzed C-H amidation of: S -tetrazines
Xiong, Huan,Gu, Yuang,Zhang, Shuning,Lu, Fengping,Ji, Qun,Liu, Lili,Ma, Peixiang,Yang, Guang,Hou, Wei,Xu, Hongtao
, p. 4692 - 4695 (2020)
An efficient, selective and scalable C-H amidation of s-tetrazines under iridium(III) catalysis is reported. This reaction features a broad substrate scope, high functional group tolerance, and air and water tolerance. This reaction also shows great potential for the rapid preparation of tri- and tetra-functional building blocks, which can be applied either in bioconjugation or synthesis of DNA-encoded library.
