561276-76-4

Basic information

• Product Name: 3-Penten-2-ol, 4-methoxy-1-[(R)-(4-methylphenyl)sulfinyl]-, (2S,3E)-
• CAS NO: 561276-76-4
• Molecular Formula: C13H18O3S
• Molecular Weight: 254.35
• Mol File: 561276-76-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Penten-2-ol, 4-methoxy-1-[(R)-(4-methylphenyl)sulfinyl]-, (2S,3E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Penten-2-ol, 4-methoxy-1-[(R)-(4-methylphenyl)sulfinyl]-, (2S,3E)-(561276-76-4)
• EPA Substance Registry System: 3-Penten-2-ol, 4-methoxy-1-[(R)-(4-methylphenyl)sulfinyl]-, (2S,3E)-(561276-76-4)

Safety Data

• Hazardous Substances Data: 561276-76-4(Hazardous Substances Data)

Upstream product

• 561276-74-2 (+)-(E,R_S)-1-(p-tolylsulfinyl)-4-methoxy-3-pentene-2-one 
• 22157-27-3 ethyl (2E)-3-methoxy-2-butenoate 
• 1519-39-7 (R)-methyl p-tolyl sulfoxide 

Relevant articles and documents

New insights into the reduction of β,δ-diketo-sulfoxides

New developments in the reduction of β,δ-diketo-sulfoxides, a reaction that affords important key intermediates for total synthesis, are described. We showed without ambiguity using NMR experiments, that the β-carbonyl group is totally enolised. This result is inconsistent with the previous hypothesis, which supposed the other tautomer (enolisation at the δ-position) as the major one. We propose a rationale to explain the side reactions occurring during the reduction of unprotected β,δ-diketo-sulfoxides and showed that judicious protection of the δ-carbonyl group gave all diastereoisomers of β-hydroxy-δ-ketosulfoxides.