56133-10-9

Upstream product

• 109208-68-6 Boc-Ala-O-COO-isoBu 
• 70396-23-5 Boc-L-alanyl-L-alanyl-L-phenylalanine methyl ester 
• 3081-24-1 H-Phe-OEt 
• 15761-38-3 L-N-Boc-Ala 
• 87892-68-0 methyl L-alanyl-L-phenylalanine trifluoroacetate 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 2280-66-2 N-tert-butyloxycarbonylalanylphenylalanine methyl ester 

Downstream Products

• 1235514-64-3 TFA*H-Ala-Ala-Phe-Lys(Z)-OMe 
• 1590380-90-7 C₂₃H₂₆N₄O₇ 
• 1590380-71-4 C₃₂H₃₇N₅O₇ 
• 1590380-72-5 C₂₅H₃₁N₅O₇ 
• 1590380-73-6 C₂₆H₃₁N₅O₈ 
• 1590380-94-1 C₂₉H₃₈N₆O₈ 
• 1590380-75-8 C₂₄H₃₀N₆O₆*C₂HF₃O₂ 
• 1590380-86-1 C₃₂H₄₄N₄O₁₀ 

Relevant academic research and scientific papers

General, Mild, and Metal-Free Synthesis of Phenyl Selenoesters from Anhydrides and Their Use in Peptide Synthesis

A mild, practical, and simple procedure for phenyl selenoesters synthesis from several anhydrides and diphenyl diselenide was developed. This transition-metal-free method provides a straightforward entry to storable Fmoc-amino acid selenoesters which are effective chemoselective acylating reagents. An application to oligopeptide synthesis was illustrated.

Furan-based locked Z -vinylogous γ-amino acid stabilizing protein α-turn in water-soluble cyclic α3γ tetrapeptides

Described here is the design, synthesis, and conformational analysis of cyclic tetrapeptides (CTPs) with α3γ architecture containing a furan-based locked Z-vinylogous amino acid (Vaa). This unnatural amino acid locks into a γ-turn that induces

Amino acid and peptide derivatives of the tylosin family of macrolide antibiotics modified by aldehyde function

Fourteen new functionally active amino acid and peptide derivatives of the antibiotics tylosin, desmycosin, and 5-O-mycaminosyltylonolide were synthesized in order to study the interaction of the growing polypeptide chain with the ribosomal tunnel. The co

Peptide derivatives of tylosin-related macrolides

Approaches to the synthesis of model compounds based on the tylosin-related macrolides desmycosin and O-mycaminosyltylonolide were developed to study the conformation and topography of the nascent peptide chain in the ribosome tunnel using specially designed peptide derivatives of macrolide antibiotics. A method for selective bromoacetylation of desmycosin at the hydroxyl group of mycinose was developed, which involves preliminary acetylation of mycaminose. The reaction of the 4″-bromoacetyl derivative of the antibiotic with cesium salts of the dipeptide Boc-Ala-Ala-OH and the hexapeptide MeOTr-Gly-Pro-Gly-Pro- Gly-Pro-OH led to the corresponding peptide derivatives of desmycosin. The protected peptides Boc-Ala-Ala-OH, Boc-Ala-Ala-Phe-OH, and Boc-Gly-Pro-Gly-Pro- Gly-Pro-OH were condensed with the C23-hydroxyl group of O- mycaminosyltylonolide.