56136-72-2Relevant academic research and scientific papers
Flavin mimetics: Synthesis and photophysical properties
R?s?dean, Dora-M.,Machida, Takashi,Sada, Kazuki,Pudney, Christopher R.,Panto?, G. Dan
, (2021/01/28)
We report the synthesis of new isoalloxazines using a microwave-assisted approach to make N-substituted-2-nitroanilines followed by one-pot reduction and condensation via Hemmerich's method. The influence of substituents on positions 7, 8, and 10 of flavin core on the optical properties is investigated. The aliphatic functionalities on N10 give rise to quantum yields of 0.7, while aromatic side-chains quench fluorescence. Relaxed geometries (DFT) of chiral and achiral derivatives have been used for TD-DFT calculations, which yielded good agreement with the experimental UV and CD data.
2-(4-ARYL-1H-IMIDAZOL-1-YL)ANILINE COMPOUNDS
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Paragraph 0074; 0077, (2015/11/27)
The present invention provides compounds that are useful as vaccine adjuvants and/or antitumor agents and methods for producing and using the same. In one particular aspect of the invention, compounds of the invention are of the formula (I) where R1, R2, R3 and Ar1 are those defined herein.
Synthesis and potent antifungal activity against Candida species of some novel 1H-benzimidazoles
Goeker, Hakan,Alp, Mehmet,Ates-Alagoez, Zeynep,Yildiz, Sulhiye
experimental part, p. 936 - 948 (2009/12/05)
(Chemical Equation Presented) A series of 47 novel N1-alkylated- 2-aryl-5(6)-substituted-1H-benzimidazoles and their three novel indole analogues were synthesized and evaluated for in vitro antifungal activities against Candida species by the tube dilution method. The results showed that compounds 79 and 80, having pyridine at the position C-2, of benzimidazoles exhibited the greatest activity with MIC values of 6.25-3.12 μg/mL. Indole analogues 108-110 have no inhibitory activity.
Synthesis and magnetic properties of new binuclear Cu(II) complexes with tridentate azomethine ligands
Burlov,Ikorskii,Uraev,Koshchienko,Vasil'chenko,Garnovskii,Borodkin,Nikolaevskii,Garnovskii
, p. 1282 - 1287 (2008/02/03)
New binuclear copper complexes of tridentate azomethine ligands with various combinations of N, O, and S donor centers were prepared by various procedures, including template synthesis. The magnetochemical data obtained for the range 2-300 K suggest the occurrence of antiferromagnetic coupling in most of these chelates. The only exception is the complex containing N-tosyl and N-ethyl donor fragments, in which the ferromagnetic exchange is observed. Nauka/Interperiodica 2006.
