56138-85-3Relevant academic research and scientific papers
Chemoselective Homologation-Deoxygenation Strategy Enabling the Direct Conversion of Carbonyls into (n+1)-Halomethyl-Alkanes
Citarella, Andrea,Holzer, Wolfgang,Ielo, Laura,Langer, Thierry,Miele, Margherita,Pace, Vittorio,Urban, Ernst,Zehl, Martin
supporting information, p. 7629 - 7634 (2020/10/12)
The sequential installation of a carbenoid and a hydride into a carbonyl, furnishing halomethyl alkyl derivatives, is reported. Despite the employment of carbenoids as nucleophiles in reactions with carbon-centered electrophiles, sp3-type alkyl halides remain elusive materials for selective one-carbon homologations. Our tactic levers on using carbonyls as starting materials and enables uniformly high yields and chemocontrol. The tactic is flexible and is not limited to carbenoids. Also, diverse carbanion-like species can act as nucleophiles, thus making it of general applicability.
Kinetics and mechanism of the dehydrohalogenation of Ar2CHCX3 and Ar2CHCHX2 by strong N-bases
Schroeder, Grzegorz,Leska, Boguslawa,Gierczyk, Blazej,Bartosz Rozalski,Brzezinski, Bogumil
, p. 173 - 179 (2007/10/03)
The kinetics and mechanism of the elimination reactions of 1,1,1- trifluoro-, 1,1,1-trichloro-, 1,1,1-tribromo-, 1,1-dichloro- and 1,1-dibromo- 2,2-bis(4-nitrophenyl)ethanes and two strong N-bases: 1,5,7- triazabicyclo[4.4.0]dec-5-ene (TBD) and 7-methyl-1
Bromination of organic molecules with polymer-supported bromine complexes
Zupan,Segatin
, p. 2617 - 2626 (2007/10/02)
Three types of bromine complexes with various polymers bearing basic units (pyridine, piperidine and piperazine) were investigated and the role of polymer matrices on reactivity was tested by three types of organic reactions: electrophilic addition, aroma
