56153-01-6

Upstream product

• 50438-75-0 2-(4-dimethylaminophenyl)ethyl alcohol 
• 17078-28-3 2-[4-(dimethylamino)phenyl]acetic acid 

Downstream Products

• 613233-61-7 (+)-octahydro-3,6α-dimethyl-3,12-epoxy-9α-(3'-(p-N,N-dimethylaminophenyl)propyl)-12H-pyrano[4,3j]-1,2-benzodioxepin-10(3H)-one 
• 613233-72-0 (+)-octahydro-3,6α-dimethyl-3,12-epoxy-9β-(3'-(p-N,N-dimethylaminophenyl)propyl)-12H-pyrano[4,3j]-1,2-benzodioxepin-10(3H)-one 
• 613233-77-5 C₂₅H₃₇NO₅ 
• 613233-78-6 (+)-octahydro-3,6α-dimethyl-3,12-epoxy-9β-(3'-(p-N,N-dimethylaminophenyl)propyl)-12H-pyrano[4,3j]-1,2-benzodioxepin-10(3H)-one 
• 2039-80-7 N,N-dimethy-4-vinylaniline 
• 63732-69-4 17-(4-dimethylamino-phenethyl)-morphinan-3-ol 

Relevant academic research and scientific papers

Structure-activity relationships of the antimalarial agent artemisinin. 8. Design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria

Artemisinin (1) and its analogues have been well studied for their antimalarial activity. Here we present the antimalarial activity of some novel C-9-modified artemisinin analogues synthesized using artemisitene as the key intermediate. Further, antileish

OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS

The invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

ARTEMISININ-BASED PEROXIDE COMPOUNDS AS BROAD SPECTRUM ANTI-INFECTIVE AGENTS

Described herein is the synthesis, bioassay results and utility of new C-9 and C-10 substituted artemisinin derivatives with easily functionalizable groups attached to the artemisinin skeleton through carbon chain or heteroatoms. Described also is the demonstration of this class of compounds for their broad-spectrum anti-parasitic activity. Certain of these analogs possess noticeable cytotoxicity deliberately focused on treatment of cancerous diseases.