50438-75-0

Basic information

• Product Name: 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL
• Synonyms: 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL, 99+%;Benzeneethanol, 4-(dimethylamino)-;4-(Dimethylamino)benzeneethanol;p-(Dimethylamino)phenethyl alcohol;2-(4-Dimetylaminophenyl)ethanol;Ccris 987;4-(N,N-dimethylamino)benzeneethanol;2-(4-(Dimethylamino)
• CAS NO: 50438-75-0
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.23
• Mol File: 50438-75-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 54-58 °C(lit.)
• Boiling Point: 284.5°Cat760mmHg
• Flash Point: 136.5°C
• Appearance: White to light brown/Crystalline Powder
• Density: 1.047g/cm³
• Vapor Pressure: 0.00139mmHg at 25°C
• Refractive Index: 1.568
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 15.07±0.10(Predicted)
• BRN: 2717032
• CAS DataBase Reference: 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL(50438-75-0)
• EPA Substance Registry System: 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL(50438-75-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 50438-75-0(Hazardous Substances Data)

Usage

Uses

2-[4-(Dimethylamino)phenyl]ethanol (4-(Dimethylamino)phenethyl alcohol) may be used as accelerator to investigate the the curing of bone cement at molecular level by electron spin resonance (ESR) spectroscopy. 2-[4-(Dimethylamino)phenyl]ethanol (4-(N,N-dimethylamino)phenethyl alcohol) may be used to compare the efficiency of different camphorquinone (CQ)/amine photo-initiating systems for the photopolymerization of a model dental resin.

General Description

2-[4-(Dimethylamino)phenyl]ethanol (4-(Dimethylamino)phenethyl alcohol) is a more effective accelerator than N,N-dimethyl-p-toluidine (TD) for bone cement curing.

InChI:InChI=1/C10H15NO/c1-11(2)10-5-3-9(4-6-10)7-8-12/h3-6,12H,7-8H2,1-2H3

Upstream product

• 100-10-7 4-dimethylamino-benzaldehyde 
• 1703-46-4 N,N-dimethyl-4-hydroxymethylaniline 
• 66379-84-8 2,2,2-trichloro-1-[4-(dimethylamino)phenyl]ethan-1-ol 
• 17078-28-3 2-[4-(dimethylamino)phenyl]acetic acid 
• 2039-80-7 N,N-dimethy-4-vinylaniline 
• 50-00-0 formaldehyd 
• 100-27-6 2-(4-nitrophenyl)ethanol 

Downstream Products

• 524743-25-7 4-(2-chloroethyl)-N,N-dimethylaniline hydrochloride 
• 104398-23-4 p-(dimethylaminophenyl)benzyl methyl sulfone 
• 6767-29-9 4-dimethylaminobenzeneacetic acid methyl ester 
• 1148144-58-4 4-((1H-benzimidazol-2-yl)methyl)-N,N-dimethylaniline 
• 98-87-3 benzylidene dichloride 
• 56153-00-5 1-chloro-2-(4-dimethylaminophenyl)ethane 
• 56153-01-6 p-(N,N-dimethylamino)phenethyl bromide 
• 139670-57-8 2-(4-dimethylaminophenyl)ethyl tosylate 
• 116308-57-7 2-(4-dimethylaminophenyl)ethyl acetoacetate 

Relevant articles and documents

OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS

The invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

One-Carbon Homologation of Primary Alcohols and the Reductive Homologation of Aldehydes Involving a Jocic-Type Reaction

(Trichloromethyl)carbinols, which are formed in one operation from either alcohols or aldehydes, can be converted into primary alcohols in a Jocic-type reaction involving LiBH4. The net result is a convenient two-step, one-carbon homologation of primary alcohols or a reductive one-carbon homologation of aldehydes featuring a broad substrate scope. The method is step-economical, and it nicely complements established one-carbon homologation strategies. (Trichloromethyl)carbinols, which are formed in one operation from either alcohols or aldehydes, can be converted into primary alcohols in a Jocic-type reaction involving LiBH4. The net result is a convenient two-step, one-carbon homologation of primary alcohols or a reductive one-carbon homologation of aldehydes featuring a broad substrate scope.

ARTEMISININ-BASED PEROXIDE COMPOUNDS AS BROAD SPECTRUM ANTI-INFECTIVE AGENTS

Described herein is the synthesis, bioassay results and utility of new C-9 and C-10 substituted artemisinin derivatives with easily functionalizable groups attached to the artemisinin skeleton through carbon chain or heteroatoms. Described also is the demonstration of this class of compounds for their broad-spectrum anti-parasitic activity. Certain of these analogs possess noticeable cytotoxicity deliberately focused on treatment of cancerous diseases.