5618-98-4

Usage

InChI:InChI=1/C17H17NO5/c19-14-8-6-12(7-9-14)10-15(16(20)21)18-17(22)23-11-13-4-2-1-3-5-13/h1-9,15,19H,10-11H2,(H,18,22)(H,20,21)/t15-/m0/s1

Upstream product

• 501-53-1 benzyl chloroformate 
• 556-02-5 ?Tyr 

Downstream Products

• 134793-38-7 [2-(4-Hydroxy-phenyl)-1-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester 
• 107155-21-5 3-(N-Carbobenzyloxyamino)-7,9-dibrom-1-oxaspiro-[4.5]-deca-6,9-dien-2,8-dion 
• 60-18-4 L-tyrosine 
• 64205-12-5 N-α-benzyloxycarbonyl-D-tyrosine 
• 13512-31-7 N-(benzyloxycarbonyl)-L-tyrosine methyl ester 
• 140844-99-1 Z-L-Tyr-L-Ile-OtBu 
• 16874-62-7 Z-L-Tyr-L-Ala-OMe 
• 2466-87-7 Z-L-Tyr-L-Val-OMe 
• 18689-47-9 Z-L-Tyr-L-Phe-OMe 
• 1108146-41-3 (S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanoate 
• 16677-09-1 Z-L-Tyr-Gly-OMe 
• 38688-48-1 4-(Benzyloxycarbonylamino-methyl)-cyclohexanecarboxylic acid 4-(2-benzyloxycarbonyl-2-benzyloxycarbonylamino-ethyl)-phenyl ester 
• 47305-80-6 4-Aminomethyl-cyclohexanecarboxylic acid 4-(2-amino-2-carboxy-ethyl)-phenyl ester 
• 134793-31-0 2-amino-3-(4-hydroxyphenyl)-N-(2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)propanamide 

Relevant academic research and scientific papers

Design and synthesis of a targeted set of aromatic amino acid derivatives for identification of new lead compounds.

A targeted set of 256 aromatic α-amino acid derivatives is described to provide new lead compounds for biological screening. The utility is exemplified by identification of ligands for the human neuromedin B (hNMB) receptor, such as compound 3 (Ki hNMB 37nM).

Composition containing a penem or carbapenem antibiotic

Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separately, either simultaneously or sequentially. The composition may be prepared by simple mixing.