5619-06-7Relevant academic research and scientific papers
Ligand-Enabled γ-C(sp3)–H Acetoxylation of Triflyl-Protected Amines
Jia, Wen-Liang,Fernández-Ibá?ez, M. ángeles
supporting information, p. 6088 - 6091 (2018/09/14)
A palladium-catalyzed γ-C(sp3)–H acetoxylation of triflyl-protected amines has been achieved. The use of pyridine or 2-alkoxyquinoline-type ligands is key to the success of this transformation. The reaction is highly diastereoselective and easily scalable, and constitutes a direct approach for the synthesis of γ-hydroxy-α-amino acids and β,γ-dihydroxy amines, which are not readily accessible by other routes.
NOVEL HDAC INHIBITORS AND METHODS OF TREATMENT USING THE SAME
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Paragraph 000189, (2017/03/21)
Disclosed herein are novel HDAC inhibitors. The HDAC inhibitors may be used in methods of treating cancer. The HDAC inhibitors may be used in methods of treating a neurological disorder.
Highly tunable arylated cinchona alkaloids as bifunctional catalysts
Quigley, Cormac,Rodriguez-Docampo, Zaida,Connon, Stephen J.
supporting information; scheme or table, p. 1443 - 1445 (2012/03/11)
We report the design and evaluation of a library of chiral bifunctional organocatalysts in which the distance between the catalytically active units can be systematically varied.
