562098-08-2

Usage

Uses

Used in Pharmaceutical Industry:
4-(Acetoxymethyl)benzeneboronic acid pinacol ester is used as a reagent for the synthesis of biologically active compounds and pharmaceutical intermediates. Its stability and versatility make it a valuable tool in the development of new drugs and therapeutic agents.
Used in Academic Research:
4-(Acetoxymethyl)benzeneboronic acid pinacol ester is used as a reagent in academic research settings for the synthesis of complex organic molecules and the study of reaction mechanisms in Suzuki-Miyaura coupling reactions.
Used in Industrial Research:
4-(Acetoxymethyl)benzeneboronic acid pinacol ester is used as a reagent in industrial research for the development of new chemical processes and the optimization of existing ones, particularly in the synthesis of pharmaceuticals and other biologically active compounds.

InChI:InChI=1/C15H21BO4/c1-11(17)18-10-12-6-8-13(9-7-12)16-19-14(2,3)15(4,5)20-16/h6-9H,10H2,1-5H3

Upstream product

• 75-36-5 acetyl chloride 
• 302348-51-2 (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol 
• 140-11-4 Benzyl acetate 
• 73183-34-3 bis(pinacol)diborane 

Relevant academic research and scientific papers

A dithiocarbamate-based H2O2-responsive prodrug for combinational chemotherapy and oxidative stress amplification therapy

Here, we report the rational design of a H2O2-responsive diethyldithiocarbamate (DTC)-based prodrug, which chelated Cu(ii) to form Cu(DTC)2 with a high anticancer activity in a tumor-microenvironment and induced oxidative stress amplification, showing superior antitumor toxicity to disulfiram.

Pd-Catalyzed Site-Selective Borylation of Simple Arenes via Thianthrenation?

Site-selective borylation of simple arenes was realized in one pot via an electrophilic thianthrenation/Pd-catalyzed borylation sequence. The key to achieve this operatically simple process is the use of Pd catalysis, which could tolerate the solvent and acidic conditions used in the thianthrenation step. This protocol features mild conditions, broad functional group tolerance, and simple manipulations, and is suitable for late-stage functionalization of a wide range of pharmaceuticals and complex bioactive molecules.

NOVEL BIPHENYL COMPOUND OR SALT THEREOF

The present invention provides a compound represented by Formula (I) or a salt thereof; an LSD1 inhibitor that contains the compound or a salt thereof as an active ingredient; a pharmaceutical composition that contains the compound or a salt thereof; and

METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1

A method for predicting a therapeutic effect of a chemotherapy using an antitumor agent comprising an LSD1 inhibitor in a cancer patient based on an expression level of INSM1 in a sample containing tumor cells isolated from the cancer patient.

ANTI-TUMOR EFFECT POTENTIATOR USING NOVEL BIPHENYL COMPOUND

An antitumor formulation comprising a biphenyl compound having LSD1 inhibitory activity or a salt thereof and one or more other antitumor agents that are administered in combination, the compound being represented by Formula (I): wherein ring A, ring B, R

NOVEL BIPHENYL COMPOUND OR SALT THEREOF

A compound or a salt thereof represented by Formula (I). An LSD1 inhibitor containing the compound or a salt thereof as an active ingredient. A pharmaceutical composition containing the compound or salt thereof. An antitumor agent containing the compound