562099-41-6

Basic information

• Product Name: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-, 1-methylethyl ester, (5S,6E)-
• CAS NO: 562099-41-6
• Molecular Formula: C28H28FNO4
• Molecular Weight: 461.533
• Mol File: 562099-41-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-, 1-methylethyl ester, (5S,6E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-, 1-methylethyl ester, (5S,6E)-(562099-41-6)
• EPA Substance Registry System: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-, 1-methylethyl ester, (5S,6E)-(562099-41-6)

Safety Data

• Hazardous Substances Data: 562099-41-6(Hazardous Substances Data)

Upstream product

• 148901-68-2 (E)-3-[2-cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-propenal 

Relevant articles and documents

Method for manufacturing optically active 5-hydroxy-3-ketoesters

The purpose of the present invention is to provide a method for manufacturing optically active 5-hydroxy-3-ketoesters with high yield and high stereoselectivity that can be used as a pharmaceutical intermediate. The purpose of the present invention is also to provide a manufacturing intermediate for a novel pharmaceutical product obtained using the method. A novel manufacturing method for obtaining an optically active 5-hydroxy-3-ketoester compound with high yield and high stereoselectivity by allowing a substituted nitrogen-containing 5-6 member heteroaromatic ring compound to coexist in the presence of an optically active binaphthol-titanium complex in an asymmetrical aldol reaction using a 1,3-diene compound; and a novel manufacturing intermediate compound having a crystalline form.

Process for the manufacture of organic compounds

A method for preparing an alkali metal salt comprising: (a) condensing a disilyloxydiene with an aldehyde in the presence of a titanium (IV) catalyst in an inert solvent to form a 5(S)-hydroxy-3-ketoester; (b) reducing the 5(S)-hydroxy-3-ketoester to a 3(