562104-03-4Relevant academic research and scientific papers
Novel 3-Arylamino- and 3-Cycloalkylamino-5,6-diphenyl-pyridazines Active as ACAT Inhibitors
Toma, Lucio,Giovannoni, Maria Paola,Vergelli, Claudia,Dal Piaz, Vittorio,Kwon, Byoung-Mog,Kim, Young-Kook,Gelain, Arianna,Barlocco, Daniela
, p. 563 - 566 (2002)
A new series of pyridazine derivatives, structurally related to the previously reported ACAT inhibitors 3-(cyclo)alkylamino-5,6-diphenyl-pyridazines, were synthesized and tested for their inhibitory properties. Substitution of the 3-alkylamino chain with a phenylamino group maintains activity. In contrast, the presence of either substituents on the phenylamino group or aliphatic rings having more or less than six carbon atoms lowers it.
