56235-33-7Relevant academic research and scientific papers
Triphosgene-mediated chlorolactamization and aminolactamization of homoallylic amines
Nishida, Yuika,Takeda, Norihiko,Miyata, Okiko,Ueda, Masafumi
, p. 787 - 798 (2017/07/27)
Two types of aminocarbonylation reaction of homoallylic amines have been developed. The treatment of homoallylic amines with triphosgene in dichloromethane led to formation of the corresponding β-chlorolactams via Prins-type cyclization of a carbamoyl chloride intermediate. For the reaction in acetonitrile, β-aminolactams were obtained via sequential Prins-type cyclization and Ritter-type reactions.
Dimethylzinc-Mediated Chlorolactamization of Homoallylic Amines with Chloroform
Nishida, Yuika,Ueda, Masafumi,Hayashi, Masataka,Takeda, Norihiko,Miyata, Okiko
supporting information, p. 22 - 25 (2016/01/26)
A novel chlorolactamization reaction of homoallylic amines has been developed. The treatment of homoallylic amines with dimethylzinc in chloroform led to the formation of the corresponding β-chlorolactams via the Prins-type cyclization of a carbamoyl chlo
Synthesis of nitrogen-containing heterocycles via ring-closing ene-ene and ene-yne metathesis reactions: An easy access to 1- and 2-benzazepine scaffolds and five- and six-membered lactams
Benedetti, Erica,Lomazzi, Michela,Tibiletti, Francesco,Palmisano, Giovanni,Penoni, Andrea,Goddard, Jean-Philippe,Fensterbank, Louis,Malacria, Max
, p. 3523 - 3533,11 (2012/12/12)
Novel regioselective ring closing ene-yne metathesis provided an efficient access to different substituted 1-benzazepine scaffolds. The reported synthetic approach could also be used as a powerful tool for the selective formation of a highly functionaliza
Michael addition of nitroalkanes to nonactivated α,β-unsaturated δ-thiolactams: reactivity, diastereoselectivity, and comparison to α,β-unsaturated δ-lactams
So?nicki, Jacek G.
experimental part, p. 1336 - 1348 (2009/04/10)
Aliphatic nitrocompounds add to nonactivated α,β-unsaturated δ-thiolactams leading to 4-nitroalkyl functionalized δ-thiolactams in good yields. The addition is a stereocontrolled process with respect to substituents at C-6, and takes place producing trans
