5626-44-8Relevant academic research and scientific papers
Stereocontrolled syntheses of kainoid amino acids from 7-azabicyclo[2.2.1] heptadienes using tandem radical addition-homoallylic radical rearrangement
Hodgson, David M.,Hachisu, Shuji,Andrews, Mark D.
, p. 8866 - 8876 (2005)
N-Boc syn-7-(2-hydroxyethyl)-4-(alkyl or aryl)sulfonyl-2-azabicyclo[2.2.1] hept-5-enes serve as precursors in syntheses of the neuroexcitants 3-(carboxymethyl)pyrrolidine-2,4-dicarboxylic acid 43, α-kainic acid 12, α-isokainic acid 14, and α-dihydroalloka
Syntheses of (±)-α-isokainic acid and (±)-α- dihydroallokainic acid using a decarboxylative Ramberg-Ba?cklund reaction
Hodgson, David M.,Hachisu, Shuji,Andrews, Mark D.
, p. 1267 - 1270 (2007/10/03)
Total syntheses of (±)-α-isokainic acid and (±)-α-dihydroallokainic acid have been achieved via tandem radical addition-homoallylic rearrangement and a decarboxylative Ramberg-Ba?cklund reaction as the key steps.
