Stereocontrolled syntheses of kainoid amino acids from 7-azabicyclo[2.2.1] heptadienes using tandem radical addition-homoallylic radical rearrangement

DOI: 10.1021/jo0513865

Source and publish data:

Journal of Organic Chemistry p. 8866 - 8876 (2005)

Update date:2022-08-05

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Authors:

Hodgson, David M.

Hachisu, Shuji

Andrews, Mark D.

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Article abstract of DOI:10.1021/jo0513865

N-Boc syn-7-(2-hydroxyethyl)-4-(alkyl or aryl)sulfonyl-2-azabicyclo[2.2.1] hept-5-enes serve as precursors in syntheses of the neuroexcitants 3-(carboxymethyl)pyrrolidine-2,4-dicarboxylic acid 43, α-kainic acid 12, α-isokainic acid 14, and α-dihydroalloka

Full text of DOI:10.1021/jo0513865

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