56268-56-5Relevant academic research and scientific papers
Palladium-catalyzed cross-coupling of benzyltitanium(IV) reagents with aryl fluorides
Li, Yan
, (2022/01/11)
The first palladium-catalyzed cross-coupling between benzyltitanium(IV) reagents with aryl fluorides is reported. A variety of diarylmethanes can be prepared in good to excellent yields by the catalyst system of PdCl2(dppf)2 associated with 1-[2-(di-tert-butylphosphanyl)phenyl]-4-methoxypiperidine. This reaction offered a highly efficient approach to diarylmethanes that are commonly found in life-changing drug molecules. Graphical abstract: [Figure not available: see fulltext.]
Gallium Dichloride-Mediated Reductive Friedel-Crafts Reaction
Hashimoto, Yukihiko,Hirata, Kazujuki,Kagoshima, Hirotaka,Kihara, Nobuhiro,Hasegawa, Masaki,Saigo, Kazuhiko
, p. 5969 - 5978 (2007/10/02)
In the presence of gallium dichloride, the reaction of carbonyl compounds or their dimethylacetals with aromatic compounds afforded Friedel-Crafts alkylated adducts in good yields.It was suggested that the adducts were obtained by way of a reduction of the carbonyl compounds or their dimethylacetals, followed by the Friedel-Crafts reaction in one-pot.This is the first organic synthetic method with gallium dichloride, low valent gallium.
Gallium dichloro-mediated reductive Friedel-Crafts reaction
Hashimoto,Hirata,Kihara,Hasegawa,Saigo
, p. 6351 - 6354 (2007/10/02)
In the presence of gallium dichloride, carbonyl compounds reacted with anisole to give alkylated anisoles in good yields. It was suggested that the adducts were obtained by way of the reduction of the carbonyl compounds followed by the Friedel-Crafts reaction in a one-pot. This is the first organic synthetic method with gallium dichloride, low valent gallium.
