562817-61-2Relevant academic research and scientific papers
Asymmetric synthesis of (+)-L-733, 060 and (+)-CP-99, 994 based on a new chiral 3-piperidinol synthon.
Huang, Pei-Qiang,Liu, Liang-Xian,Wei, Bang-Guo,Ruan, Yuan-Ping
, p. 1927 - 1929 (2007/10/03)
[reaction: see text] Selective and potent neurokinin substance P receptor antagonists (+)-L-733, 060 (1) and (+)-CP-99, 994 (2) have been synthesized starting from a new (3S)-piperidinol synthon derived from l-glutamic acid. The methods featured a C-2 reg
