562869-99-2

Upstream product

• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 247158-79-8 5-Bromo-2-methoxymethyl-6-phenylpyridazin-3-one 
• 90766-97-5 5-bromo-6-phenylpyridazin-3(2H)-one 

Downstream Products

• 562869-98-1 2-methoxymethyl-5-(3-oxo-3-phenylpropenyl)-6-phenyl-3-pyridazinone 

Relevant academic research and scientific papers

Pyridazine derivatives. Part 33: Sonogashira approaches in the synthesis of 5-substituted-6-phenyl-3(2H)-pyridazinones

Several 6-phenyl-3(2H)-pyridazinones bearing different alkynyl groups at position 5 have been prepared by a palladium-catalysed Sonogashira cross-coupling reaction. An interesting base-promoted electronically permitted isomerization has been observed duri