56312-14-2

Basic information

• Product Name: 1,8-OCTANE DIISOTHIOCYANATE
• Synonyms: 1,8-OCTANE DIISOTHIOCYANATE;1,8-Diisothiocyanatooctane;1,8-Octanediyldiisothiocyanate;Octamethylenebisisothiocyanate;1,8-Octane diisothiocyate
• CAS NO: 56312-14-2
• Molecular Formula: C10H16N2S2
• Molecular Weight: 228.38
• Mol File: 56312-14-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 158 °C
• Flash Point: 178.1°C
• Appearance: /
• Density: 1.07
• Vapor Pressure: 6.62E-05mmHg at 25°C
• Refractive Index: 1.542
• CAS DataBase Reference: 1,8-OCTANE DIISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-OCTANE DIISOTHIOCYANATE(56312-14-2)
• EPA Substance Registry System: 1,8-OCTANE DIISOTHIOCYANATE(56312-14-2)

Safety Data

• HazardClass: IRRITANT-HARMFUL
• Hazardous Substances Data: 56312-14-2(Hazardous Substances Data)

Usage

General Description

1,8-Octane diisothiocyanate is a chemical compound with the molecular formula C10H16N2S2. It is a member of the class of organic compounds known as isothiocyanates, which are sulfur-containing organic compounds commonly used in organic synthesis and in the manufacturing of pesticides and pharmaceuticals. 1,8-Octane diisothiocyanate is a colorless to pale yellow liquid with a pungent odor, and it is primarily used as a crosslinking agent in the production of polymers and coatings. It is known to be a skin and respiratory irritant and can cause skin sensitization upon contact. Due to its potential health hazards, proper safety precautions should be taken when handling this chemical, including the use of protective equipment and proper ventilation.

InChI:InChI=1/C10H16N2S2/c13-9-11-7-5-3-1-2-4-6-8-12-10-14/h1-8H2

Upstream product

• 2162-99-4 1,8-dichlorooctane 
• 333-20-0 potassium thioacyanate 
• 373-44-4 1,8-diaminooctan 

Relevant articles and documents

ISOTHIOCYANATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

Provided herein are compositions of matter and pharmaceutical compositions thereof, for use in inhibiting the growth of various microbial pathogens, including bacteria, fungi, protozoa, and viral pathogens. Also provided herein are methods of treating microbial diseases/infections and cancer with the compositions. The compositions are additionally useful in wood preservation and food preservation by inhibition of microbial growth.

Synthesis and biological evaluation of ureido and thioureido derivatives of 2-amino-2-deoxy-D-glucose and related aminoalcohols as N-acetyl-β-D-hexosaminidase inhibitors

Ureido and thioureido derivatives of 2-acetamido-2-deoxy-β-D-glucose, 1-amino-1-deoxy-D-glucitol and 2-(2-aminoethoxy)ethanol were prepared as N-acetyl-β-D-hexosaminidase (NAHase) inhibitors and were evaluated on Trichomonas vaginalis NAHase. Although none showed complete inhibition of the enzyme at 100 μM, 1-amino-1-deoxy-D-glucitol derivatives acted as competitive inhibitors of the NAHase of T. vaginalis. Copyright (C) 1998 Elsevier Science Ltd.