5633-65-8Relevant academic research and scientific papers
Palladium catalyzed regioselective elimination-hydrocarbonylation of propargylic alcohols
Yuan, Yuan,Jia, Minqiang,Zhang, Wanli,Ma, Shengming
, p. 7938 - 7941 (2019)
A straightforward approach to synthesizing substituted 1,3-alkadien-2-yl carboxylic acids starting from readily available propargylic alcohols was developed. Based on mechanistic studies, the reaction was found to proceed via regioselective hydrocarbonylation of the C-C triple bonds of the in situ formed 1,3-enyne intermediates, providing 1,3-alkadien-2-yl carboxylic acids with a very high selectivity.
