5635-43-8Relevant academic research and scientific papers
Formal [5+1] annulation reactions of dielectrophilic peroxides: Facile access to functionalized dihydropyrans
Zhong, Chen,Yin, Qi,Zhao, Yukun,Li, Qinfeng,Hu, Lin
supporting information, p. 13189 - 13192 (2020/11/09)
A general [5+1] annulation reaction, which utilized 4-bromo- or 4-mesyloxy-but-2-enyl peroxides as unique five-atom bielectrophilic synthons to participate in the C-C and the subsequent umpolung C-O bond-forming reactions with C1 nucleophiles, has been developed for the facile synthesis of 2,2-disubstituted dihydropyrans in high yields under mild basic conditions. The dihydropyrans, which are readily prepared on a gram scale by this new method, can be flexibly transformed into the biologically important tetrahydropyrans and pyranones in 1-2 steps.
On the dichotomic reactivity of lithiated styrene oxide: A computational and multinuclear magnetic resonance investigation
Capriati, Vito,Florio, Saverio,Perna, Filippo Maria,Salomone, Antonio,Abbotto, Alessandro,Amedjkouh, Mohamed,Nilsson Lill, Sten O.
scheme or table, p. 7958 - 7979 (2010/03/31)
A multinuclear magnetic resonance investigation, supported by density functional theory calculations, has been synergically used to investigate the configurational stability, reactivity and aggregation states of a-lithiated styrene oxide in THF at 173 K.
