5636-53-3Relevant academic research and scientific papers
THERAPEUTIC FLUOROETHYL UREAS
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Page/Page column 14, (2008/06/13)
Compounds of the formula or a pharmaceutically acceptable salt thereof or a tautomer thereof, wherein A and B are as described herein, are useful for treating conditions afflicting mammals.
In search of new chemical entities with spermicidal and anti-HIV activities
Srivastava, Seema,Bajpai, Lakshmi Kant,Batra, Sanjay,Bhaduri, Amiya P.,Maikhuri,Gupta, Gopal,Dhar
, p. 2607 - 2613 (2007/10/03)
Several compounds belonging to 2-isoxazolines (4,5a-c), isoxazoles (3,6a-c) and 1-amino-1-cycloalkyl-2-substituted phenyl ethanes (16-18,a-e) have been synthesised and found to possess spermicidal activity. Out of these a couple of compounds (5a and 6a) exhibit anti-HIV activity. (C) Elsevier Science Ltd.
Convenient Access to Primary Amines by Employing the Barbier-Type Reaction of N-(Trimethylsilyl)imines Derived from Aromatic and Aliphatic Aldehydes
Gyenes, Ferenc,Bergmann, Kathryn E.,Welch, John T.
, p. 2824 - 2828 (2007/10/03)
A new versatile preparation of primary amines via benzylation of aromatic and aliphatic aldimines is described. Sonochemical and traditional methods for generation of the reactive intermediates are compared and contrasted. Competitive reactions were analyzed via free energy relationships to support the proposed alkylative mechanism.
