56360-93-1Relevant academic research and scientific papers
Stereochemical studies of adrenergic drugs. Diastereomeric 2 amino 1 phenylcyclobutanols
Miller,Hsu,Salman,Patil
, p. 180 - 184 (1976)
The synthesis of the cis and trans 2 amino 1 phenylcyclobutanols 2 and 3 is described. The results of the potentiation of the action of (-) norepinephrine by these two compounds are discussed.
Concurrent Formation of N-H Imines and Carbonyl Compounds by Ruthenium-Catalyzed C-C Bond Cleavage of β-Hydroxy Azides
Lee, Jeong Min,Bae, Dae Young,Park, Jin Yong,Jo, Hwi Yul,Lee, Eunsung,Rhee, Young Ho,Park, Jaiwook
supporting information, p. 4608 - 4613 (2020/06/05)
A commercial cyclopentadienylrutenium dicarbonyl dimer ([CpRu(CO)2]2) efficiently catalyzes the formation of N-H imines and carbonyl compounds simultaneously from β-hydroxy azides via C-C bond cleavage under visible light. Density functional theory calculations for the cleavage reaction support the mechanism involving chelation of alkoxy azide species and liberation of nitrogen as the driving force. The synthetic utility of the reaction was demonstrated by a new amine synthesis promoted by chemoselective allylation of imine and synthesis of isoquinoline.
