56395-86-9

Upstream product

• 109087-14-1 trans-2-(aminomethyl)cyclohexanol 
• 108-24-7 acetic anhydride 
• 63301-31-5 trans-2-cyanocyclohexanol 
• 110-83-8 cyclohexene 
• 31413-48-6 cis-2-methyl-4a,5,6,7,8,8a-hexahydro-4H-1,3-benzoxazine 

Downstream Products

• 855930-63-1 N-(2-oxo-cyclohexylmethyl)-acetamide 
• 98516-18-8 (1S,2S)-2-Ethylaminomethyl-cyclohexanol 
• 126675-19-2 (1R,2R)-2-Cyclohexylaminomethyl-cyclohexanol 
• 126675-20-5 (1R,2R)-2-(Isopropylamino-methyl)-cyclohexanol 
• 109087-13-0 (+/-)-cis-2-aminomethylcyclohexanol 
• 855414-64-1 [2-(acetylamino-methyl)-1-hydroxy-cyclohexyl]-acetic acid ethyl ester 

Relevant academic research and scientific papers

trans-2-Cyanocycloalkanols: Versatile Synthons for Alicyclic cis- and trans-1,3-Amino Alcohols

From trans-2-hydroxycyclopentanecarbonitrile (1) and trans-2-hydroxycyclohexanecarbonitrile (2), a number of trans-2-aminomethylcycloalkanols are prepared by reductive alkylation.Inversion of trans-N-acylaminocycloalkanols by treatment with thionyl chlori

STEREOCHEMICAL STUDIES, 80. CYCLIC AMINOALCOHOLS AND RELATED COMPOUNDS, 26. PREPARATION OF CIS-2-(ALKYLAMINOMETHYL)- AND (ARALKYLAMINOMETHYL)-1-CYCLANOLS FROM OLEFINS VIA THE 5,6-DIHYDRO-4H-1,3-OXAZINE DERIVATIVES

Cycloalkenes were allowed to react with N-(hydroxymethyl)alkyl- or -arylamides in the presence of concentrated sulfuric acid in glacial acetic acid, using the method suggested by Schmidt.In the majority of cases, the reaction yielded the corresponding cis