56407-48-8Relevant academic research and scientific papers
7 N amidinocephalosporins
Altman,Karoly,Maoz
, p. 627 - 630 (1975)
7 Aminocephalosporanic acid tert butyl ester reacts quantitatively at -20°C with iminium chlorides to give amidino derivatives. Removal of the tert butyl protecting group with trifluoroacetic acid and treatment with 1 equiv of triethylamine yield the corresponding zwitterions. These compounds were less active than their penicillin analogs.
