56427-63-5

Usage

Uses

Used in Pharmaceutical Manufacturing:
Benzoic acid, 2-(bromomethyl)-4-methoxy-, ethyl ester is used as an intermediate in the synthesis of pharmaceuticals for its reactivity and ability to form specific chemical bonds that are essential in creating certain medications.
Used in Organic Synthesis:
In the field of organic chemistry, Benzoic acid, 2-(bromomethyl)-4-methoxy-, ethyl ester is utilized as a building block for the creation of more complex organic molecules. Its unique structure allows it to participate in various chemical reactions, contributing to the development of new chemical entities and materials.
Used in Drug Development:
Benzoic acid, 2-(bromomethyl)-4-methoxy-, ethyl ester's properties make it a valuable asset in the research and development of new drugs. Its reactivity and structural features can be leveraged to design and synthesize novel pharmaceutical agents with potential therapeutic applications.
Overall, Benzoic acid, 2-(bromomethyl)-4-methoxy-, ethyl ester is a versatile chemical intermediate that finds application across various industries, particularly in the pharmaceutical sector, where it contributes to the advancement of medicine and the development of innovative treatments.

Upstream product

• 56427-62-4 ethyl 4-methoxy-2-methylbenzoate 

Downstream Products

• 867296-78-4 (RS)-2-ethoxycarbonyl-2-(2-(ethoxycarbonyl)-5-methoxybenzyl)-5-methoxy-1-indanone 
• 55690-26-1 4-(2-carboxy-5-methoxybenzyloxy)phenylacetic acid 
• 1022984-18-4 5-methoxy-2-(4-dimethylaminophenyl)-2,3-dihydroisoindol-1-one 
• 867296-82-0 (RS)-2-ethoxycarbonyl-2-(2-(ethoxycarbonyl)-5-methoxybenzyl)-6-methoxy-1-indanone 
• 1089667-05-9 5-methoxy-2-(4-nitrophenyl)-2,3-dihydro-isoindol-1-one 

Relevant academic research and scientific papers

Synthesis of benzothiophenones and naphthothiophenone as anticholinesterases

Since AChE and BuChE belong to the same serine hydrolazes, we designed and synthesized compounds 1-6 as anticholinesterases and measured their inhibition poteucies on ChEs. 7-Methoxy-3H-benzo[c]thiophen-1-one 4, 4,6-dibromo-5,7- methoxy-3H-benzo[c]thiophe

ISOINDOLINE COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES

Disclosed is a compound of Formula (I) in which W and R1-R6 are defined herein. Also disclosed is a method of treating spinal muscular atrophy, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced directly or indirectly by mutation or frameshift.

ISOINDOLONES WITH HIGH BINDING AFFINITY TO BETA-AMYLOID AGGREGATES AND FIBRILS, AND ITS USE AND PREPARATION METHOD

The present invention relates to isoindolone compounds having high binding affinity to beta-amyloid fibrils, thereby being useful for an early diagnosis of degenerative cerebral diseases including dementia, and prevention and treatment of such diseases, i

[18F]-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of β-amyloid fibrils

In this study a novel series of isoindol-1-one and isoindol-1,3-dione derivatives for β-amyloid-specific binding agents is described. Twelve compounds were synthesized and evaluated via a competitive binding assay with [125I]TZDM against β-amyl

Ferroelectric liquid crystals induced by dopants with axially chiral 2,2′-spirobiindan-1,1′-dione cores

The axially chiral dopants (R)-5,5′-, 5,6′-, and 6,6′-diheptyloxy-2,2′-spirobiindan-1,1′-dione ((R)-2, -3, and -4) were synthesized in optically pure form, and their absolute configurations were assigned by the exciton chirality method using circular dich

6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives

6,11-Dihydrodibenz[b,e]oxepin-acetic acids and derivatives having the general formula STR1 are prepared by multi-step sequences. X is C=O, CHCl, CHBr, CH2 or CHOR4 ; Y is alkyl or alkoxy of 1 to 4 carbon atoms, halogen or trifluoromethyl; n is 0, 1, 2 or 3; Z is COOR5, CH2 OR5, CONR25 or CONHOR5 ; and R1 -R5 are hydrogen or alkyl of 1 to 4 carbon atoms. These compounds and the physiologically tolerable salts thereof are useful as antiinflammatory and analgesic agents.

Method of treating dermal inflammations

A method of treating dermal inflammation by topically administering to a patient an effective amount of a 6,11-dihydrodibenz[b,e]oxepinalkanoic acid, physiologically tolerable salt thereof, derivative thereof, or diacid precursor thereof is described.