56431-03-9Relevant academic research and scientific papers
Photo-induced phosphorus radical involved semipinacol rearrangement reaction: Highly synthesis of γ-oxo-phosphonates
Wang, Chunhai,Huang, Xiaoling,Liu, Xueting,Gao, Suqian,Zhao, Bin,Yang, Shangdong
, p. 677 - 680 (2019/08/27)
Hydroxyphosphoric acids display the unique biological activities, and they have some attractive prospects as clinical drug moleculars. Herein, a new approach for the synthesis of γ-oxo-phosphonates (the precursor of hydroxyphosphoric acid) has been established through the semipinacol rearrangement tactic involved the photo-induced phosphorus radical process. Most important, this transformation is avoid of the external oxidants, and occurs very well under the sunlight irradiation, meanwhile the γ-oxo-phosphonate was easily derivatized to obtain γ-hydroxyphosphoric acid, thus highlights the synthesis value of this method.
Iron-promoted difunctionalization of alkenes by phenylselenylation/1,2-aryl migration
Wu, Ping,Wu, Kaikai,Wang, Liandi,Yu, Zhengkun
supporting information, p. 5450 - 5453 (2017/11/06)
Iron-promoted difunctionalization of α,α-diaryl and α-aryl-α-alkyl allylic alcohols has been efficiently achieved by means of N-(phenylseleno)phthalimide (N-PSP) under mild conditions. An in situ generated phenylselenium cation (PhSe+) was added to the ol
Alpha-substituted benzhydrol derivatives
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, (2008/06/13)
The invention relates to new α-substituted benzhydrols and pharmaceutically acceptable acid addition salts or quaternary ammonium salts thereof with enzyme promoting or inhibiting effects;
α-Substituted benzhydrol derivatives and a process for the preparation thereof
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, (2008/06/13)
A compound of the formula: STR1 wherein Z is ethyl or vinyl, R1 and R2 are hydrogen, lower alkyl, lower alkenyl or trihalomethyl, R3 and R4 are hydrogen, lower alkyl, lower alkenyl, trihalomethyl, cyclopentyl, benzyl or phenyl, and R5 is lower alkyl, lower alkenyl, trihalomethyl, cyclopentyl, benzyl, or phenyl with the proviso that where R1, R2, R3 and R4 each is hydrogen, R5 is not methyl attached to the 4-position of the benzene ring, or a pharmaceutically acceptable acid addition or quaternary ammonium salt thereof is disclosed as effective in the regulation of the liver microsomal enzyme system.
