56434-95-8

Upstream product

• 21943-76-0 4-allyl-4-methyl-3-phenyl-4H-isoxazol-5-one 

Downstream Products

• 107112-71-0 allyl-2 ethyl-4 methyl-2 phenyl-3 2H-pyrrole 
• 71065-31-1 allyl-2 methyl-2 diphenyl-3,5 2H-pyrrole 
• 10273-90-2 2-phenyl-3-methylpyridine 
• 3274-53-1 3,5-dimethyl-2-phenyl-1H-pyrrole 
• 107112-80-1 3-((2S,5R)-2-Methyl-3,5-diphenyl-2,5-dihydro-1H-pyrrol-2-yl)-propan-1-ol 
• 107112-80-1 3-((2S,5S)-2-Methyl-3,5-diphenyl-2,5-dihydro-1H-pyrrol-2-yl)-propan-1-ol 
• 107112-73-2 (2S,5R)-2-Allyl-2-methyl-3,5-diphenyl-2,5-dihydro-1H-pyrrole 
• 107112-73-2 (2S,5S)-2-Allyl-2-methyl-3,5-diphenyl-2,5-dihydro-1H-pyrrole 
• 107112-82-3 3-(2-Methyl-3,5-diphenyl-2H-pyrrol-2-yl)-propan-1-ol 
• 107112-83-4 3-(4-Ethyl-2-methyl-3-phenyl-2,5-dihydro-1H-pyrrol-2-yl)-propan-1-ol 
• 107112-85-6 ethyl-2 methyl-8 phenyl-1 dehydro-1,2 pyrrolizidine 
• 107112-72-1 allyl-2 ethyl-4 methyl-2 phenyl-3 Δ-3-pyrroline 
• 107112-84-5 allyl-5 ethyl-4 methyl-2 phenyl-3 pyrrole 
• 79402-66-7 2-allyl-2-methyl-4-phenyl-Δ³-oxazolin-5-one 

Relevant academic research and scientific papers

Synthesis of 2H-Azirines by Iridium-Catalyzed Decarboxylative Ring Contraction of Isoxazol-5(4H)-ones

A phosphine-free iridium-catalyzed reaction of isoxazol-5(4H)-ones (isoxazolones) has been developed, and affords 2H-azirines through decarboxylation and ring contraction. This method provides an efficient and environmentally benign protocol which could replace the conventional approaches used to synthesize 2H-azirines.

Ruthenium-Catalyzed Synthesis of 2H-Azirines from Isoxazolinones

2H-Azirines are synthetically versatile, highly strained, three-membered heterocycles containing an imino double bond. We report their efficient Ru-catalyzed synthesis using low catalyst loadings under neutral conditions from isoxazolinone substrates, whi