56438-39-2Relevant academic research and scientific papers
Gold-Catalyzed Rearrangement of Alkynyl Donor-Acceptor Cyclopropanes to Construct Highly Functionalized Alkylidenecyclopentenes
Chen, Huiyu,Zhang, Jing,Wang, David Zhigang
supporting information, p. 2098 - 2101 (2015/05/13)
A gold-catalyzed 1,7-addition-cyclization-elimination cascade sequence performed on a range of alkynyl-substituted donor-acceptor-type cyclopropanes provides facile entry to highly functionalized exo-alkylidenecyclopentenes under very mild conditions. Iso
PROPARGYL ORGANOMETALLIC COMPOUNDS. II. ALKYLATION OF SODIUM DERIVATIVES OF 1-ALKYL-1-ARYL-2-ALKYNES IN LIQUID AMMONIA
Libman, N. N.,Sevryukov, Yu. P.
, p. 68 - 75 (2007/10/02)
In most cases the alkylation of the sodium derivatives of 1-phenyl-1-alkyl-2-alkynes by methyl, ethyl, isopropyl, and tert-butyl bromides in liquid ammonia takes place preferentially at the sp2-hybridized carbon atom, and this leads to the formation of the corresponding acetylenes.The regioselectivity of the reaction is explained by the greater softness of the trigonal atom of the ambident propargyl anion and its smaller screening by the solvate shell compared with the diagonal atom.
