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Bromo-PEG4-t-butyl ester is a PEG (polyethylene glycol) linker that features a bromide group and a t-butyl protected carboxyl group. This molecule is designed to enhance solubility in aqueous media due to the hydrophilic PEG spacer. The bromide (Br) acts as an excellent leaving group for nucleophilic substitution reactions, while the t-butyl protected carboxyl group can be deprotected under acidic conditions, making it a versatile compound for various applications.

564476-32-0

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564476-32-0 Usage

Uses

Used in Pharmaceutical Industry:
Bromo-PEG4-t-butyl ester is used as a building block for the synthesis of bioconjugates and drug delivery systems. The hydrophilic PEG spacer improves the solubility and stability of the final product, while the bromide group facilitates the attachment of various molecules through nucleophilic substitution reactions. The t-butyl protected carboxyl group allows for controlled deprotection under specific conditions, enabling the precise design of pharmaceutical compounds.
Used in Bioconjugation:
Bromo-PEG4-t-butyl ester is used as a bioconjugation agent for the attachment of biologically active molecules, such as peptides, proteins, or small molecules, to other biomolecules or surfaces. The bromide group serves as a reactive handle for the attachment process, while the PEG spacer provides a hydrophilic environment that can reduce aggregation and improve the overall stability of the bioconjugate.
Used in Drug Delivery Systems:
Bromo-PEG4-t-butyl ester is used as a component in the design of drug delivery systems, such as nanoparticles or micelles, for targeted drug delivery. The PEG spacer enhances the solubility and biocompatibility of the delivery system, while the bromide group allows for the attachment of therapeutic agents through nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions, enabling the release of the drug in a controlled manner, such as in the acidic environment of tumor cells.
Used in Chemical Synthesis:
Bromo-PEG4-t-butyl ester is used as an intermediate in the synthesis of various chemical compounds, particularly those requiring a PEG-based linker with a reactive bromide group and a protected carboxyl group. The versatility of this molecule allows for its use in a wide range of applications, from the development of new pharmaceuticals to the creation of advanced materials with specific properties.

Check Digit Verification of cas no

The CAS Registry Mumber 564476-32-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,6,4,4,7 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 564476-32:
(8*5)+(7*6)+(6*4)+(5*4)+(4*7)+(3*6)+(2*3)+(1*2)=180
180 % 10 = 0
So 564476-32-0 is a valid CAS Registry Number.

564476-32-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 15-Bromo-4,7,10,13-tetraoxapentadecanoic acid tert-butyl ester

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:564476-32-0 SDS

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