56472-04-9

Basic information

• Product Name: 5-nitroso-2-phenylpyrimidine-4,6-diamine
• CAS NO: 56472-04-9
• Molecular Formula: C₁₀H₉N₅O
• Molecular Weight: 215.2114
• Mol File: 56472-04-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 346.7°C at 760 mmHg
• Flash Point: 163.5°C
• Density: 1.52g/cm³
• Vapor Pressure: 5.64E-05mmHg at 25°C
• Refractive Index: 1.744
• CAS DataBase Reference: 5-nitroso-2-phenylpyrimidine-4,6-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-nitroso-2-phenylpyrimidine-4,6-diamine(56472-04-9)
• EPA Substance Registry System: 5-nitroso-2-phenylpyrimidine-4,6-diamine(56472-04-9)

Safety Data

• Hazardous Substances Data: 56472-04-9(Hazardous Substances Data)

Usage

General Description

5-nitroso-2-phenylpyrimidine-4,6-diamine is a chemical compound that belongs to the class of pyrimidine derivatives. It is a nitrosamine compound, which means it contains a nitroso group attached to a secondary amine group. The compound has potential applications in the field of medicinal chemistry, as it has been studied for its potential as an anticancer agent. Additionally, nitrosamines have also been studied for their potential role as mutagens and carcinogens, and their presence in certain foods and consumer products has been a topic of concern. Further research is needed to fully understand the properties and potential uses of 5-nitroso-2-phenylpyrimidine-4,6-diamine, as well as its potential risks and hazards.

Upstream product

• 109-06-8 α-picoline 
• 7152-36-5 isonitrosomalononitrile benzamidine salt 
• 104-90-5 5-ethyl-2-methyl-pyridine 

Downstream Products

• 29984-62-1 4-amino-2-phenyl-7(8H)-pteridinone 
• 29984-62-1 4-amino-2-phenyl-pteridine-7-one 
• 30724-65-3 5-phenyl-6H-[1,2,5]oxadiazolo[3,4-d]pyrimidin-7-one 
• 59341-33-2 5-phenyl-4⁽⁶⁾,7-dihydro-[1,2,5]oxadiazolo[3,4-d]pyrimidine 
• 59341-32-1 5-phenyl-6H-[1,2,5]oxadiazolo[3,4-d]pyrimidine-7-thione 
• 30787-98-5 N-(5-phenyl-[1,2,5]oxadiazolo[3,4-d]pyrimidin-7-yl)-benzamide 
• 23691-97-6 N-(5-phenyl-6,7-dihydro-[1,2,5]oxadiazolo[3,4-d]pyrimidin-7-yl)-acetamide 
• 30720-60-6 N-(5-phenyl-[1,2,5]oxadiazolo[3,4-d]pyrimidin-7-yl)-acetamide 
• 59341-30-9 N-(5-phenyl-[1,2,5]oxadiazolo[3,4-d]pyrimidin-7-yl)-toluene-4-sulfonamide 
• 59341-29-6 5-phenyl-7-pyrrolidin-1-yl-[1,2,5]oxadiazolo[3,4-d]pyrimidine 
• 59341-31-0 7-ethylsulfanyl-5-phenyl-[1,2,5]oxadiazolo[3,4-d]pyrimidine 
• 1501-45-7 2-phenyl-7⁽⁹⁾H-purin-6-ylamine 
• 10570-18-0 4-amino-7-oxo-2-phenyl-7,8-dihydro-pteridine-6-carboxylic acid 2-morpholin-4-yl-ethylamide 
• 30720-36-6 5-phenyl-[1,2,5]oxadiazolo[3,4-d]pyrimidin-7-ylamine 

Relevant articles and documents

Nucleosides part LXVI I[1]: Synthesis of 4-amino-7(8H) pteridinone-N8-nucleosides-structural analogs of adenosine

Various 4-amino-7(8H)pteridones (6, 12, 14, 15, 20, 22) have been glycosylated with 1-chloro-2'-deoxy-D-ribofuranose derivatives (25, 26) applying the new DBU-salt method to form the N8-2'-deoxy-D-ribofuranosides (27-36) which can be regarded as 2'-deoxyadenosine analogs. Analogously reacted the 2-N,N-dimethyl-amino-methyleneimino-7(8H)pteridones (43-48) to give preferentially the corresponding N8-ss-D-anomers (49-55). Ribosylation with 1-bromo-2,3,5-tri-O-benzoyl-a-D-ribofuranose (56) proceeded as well with 6, 12, 15, 45, and 46 to yield to N8-ss-D-ribofuranosides 57-61. Sugar deprotection led to the free N8-2'-deoxy-ss-D-ribofuranosides 37-42 and N8-ss-D-ribofurano-sides 62-65, respectively. Glycosylations via the silyl-method under Vorbruggen conditions led with 6, 12 and 15 to the same results, however, 4-amino-6-phenyl-7(8H)pteridone (14) reacted differently forming the N1-ss-D-ribofuranosides (71, 79) and the N1-2'-deoxy - and ss-D-ribofuranosides 73, 74, 77, 78. The assignments of the structures have been achieved by 1H-NMR- and UV-spectra. C,H,N-elemental analyses account for the composition.