56473-91-7 Usage
Uses
Used in Pharmaceutical Industry:
Furo[3,2-b]pyridine-5-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds for its potential therapeutic applications. Its unique structure and functional groups enable the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
Furo[3,2-b]pyridine-5-carboxylic acid is utilized as a building block in the synthesis of agrochemicals, such as pesticides and herbicides. Its versatile chemical properties allow for the creation of novel compounds with enhanced performance and selectivity in agricultural applications.
Used in Medicinal Chemistry Research:
Furo[3,2-b]pyridine-5-carboxylic acid serves as a valuable research tool in medicinal chemistry, providing insights into the design and synthesis of new drug candidates. Its unique structure and functional groups facilitate the exploration of novel chemical space and the optimization of drug-like properties.
Used in Organic Synthesis:
Furo[3,2-b]pyridine-5-carboxylic acid is employed as a versatile building block in organic synthesis, enabling the construction of complex organic molecules with diverse applications. Its unique structure and reactivity contribute to the development of innovative synthetic strategies and methodologies.
Used in Drug Discovery:
Furo[3,2-b]pyridine-5-carboxylic acid plays a crucial role in drug discovery, offering a platform for the identification and optimization of new bioactive compounds. Its potential biological activities and unique structural features make it an attractive starting point for the development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 56473-91-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,4,7 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 56473-91:
(7*5)+(6*6)+(5*4)+(4*7)+(3*3)+(2*9)+(1*1)=147
147 % 10 = 7
So 56473-91-7 is a valid CAS Registry Number.
56473-91-7Relevant academic research and scientific papers
GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTORS
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Paragraph 00339-00340, (2016/07/05)
The present invention relates to novel geminal substituted quinuclidine amide compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of α7- nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
Furopyridines. XVII [1]. Cyanation, chlorination and nitration of furo[3,2-b]pyridine N-oxide
Shiotani, Shunsaku,Taniguchi, Katsunori
, p. 1051 - 1056 (2007/10/03)
The N-oxide 2 of furo[3,2-b]pyridine (1) was cyanated by the Reissert-Henze reaction with potassium cyanide and benzoyl chloride to give 5-cyano derivative 3, which was converted to the carboxamide 4, carboxylic acid 5, ethyl ester 6 and ethyl imidate 8. Chlorination of 2 with phosphorus oxychloride yielded 2-9a, 3- 9b, 5- 9c and 7-chloro derivative 9d. Reaction of 9d with sodium methoxide, pyrrolidine, N,N-dimethylformamide and ethyl cyanoacetate afforded 7-methoxy- 10, 7-(1-pyrrolidyl)- 11 and 7-dimethylaminofuro[3,2-b]pyridine (14) and 7-(1-cyano-1-ethoxy-carbonyl)methylene-4,7-dihydro-furo[3,2-b]pyridine (12). Nitration of 2 with a mixture of fuming nitric acid and sulfuric acid gave 2-nitrofuro[3,2-b]pyridine N-oxide (15).
