56473-92-8

Usage

Uses

Used in Pharmaceutical Industry:
Thieno[3,2-b]pyridine-5-carboxylic acid is used as a key intermediate in the synthesis of novel derivatives of echinomycin, an antibiotic. It serves as a replacement chromophore in the study of the biosynthesis process by Streptomyces echinatus, contributing to the development of new and potentially more effective antibiotic agents.

Upstream product

• 56473-97-3 3-azidothiophene-2-carbaldehyde 
• 127-17-3 2-oxo-propionic acid 
• 56489-01-1 3-aminothiophene 2-carboxaldehyde 
• 113-24-6 sodium pyruvate 
• 600-22-6 pyruvic acid methyl ester 
• 170861-45-7 (3-aminothiophen-2-yl)methanol 
• 22288-78-4 Methyl 3-aminothiophene-2-carboxylate 

Relevant academic research and scientific papers

BICYCLIC HETEROAROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS

The present disclosure describes bicyclic heteroaromatic carboxamide derivatives of formula (I), as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.

ARYL SUBSTITUTED OLEFINIC COMPOUNDS AS PDE10A INHIBITORS

The present invention provides aryl substituted olefinic compounds as Phosphodiesterase 1 0A (PDE 1 0A) inhibitors. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders by inhibiting Phospho

DIARYL 5,6-FUSED HETEROCYCLIC ACIDS AS LEUKOTRIENE ANTAGONISTS

Compounds having the formula I: STR1 are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

Furo[3,2-b]pyridines and thieno[3,2-b]pyridines as inhibitors of leukotriene biosynthesis

Compounds having the formula I: STR1 are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomemlar