56478-90-1Relevant academic research and scientific papers
Synthesis and behaviour of 2-(furan-2-yl)vinyl-4H-3,1-benzoxazin-4-one towards nitrogen and carbon nucleophiles
El-Badry, Yaser A.,Anter, Naglaa M.,El-Hashash, Mahr A.
, p. 1574 - 1583 (2015/02/02)
A convenient new procedure for the synthesis of 2-(furan-2-yl)vinyl-4H-3,1-benzoxazin-4-one 4 is reported. Reaction of the respective benzoxazinone with various nitrogen nucleophiles affords 3-substituted quinazolinone and benzamide derivatives. Benzoxazinone 4 is converted to 4(3H)-quinazolinone followed by acylation, chlorination, and alkylation, which also is catalytically hydrogenated.
