56495-00-2Relevant academic research and scientific papers
2-aminobenzimidazole derivatives strongly inhibit and disperse Pseudomonas aeruginosa biofilms
Frei, Reto,Breitbach, Anthony S.,Blackwell, Helen E.
, p. 5226 - 5229 (2012/07/03)
Bacterial biofilms are exceptionally difficult to clear using traditional antibiotics and constitute a significant health threat. 2-Aminobenzimidazole derivatives (see scheme) are capable of strongly inhibiting the growth of and dispersing Pseudomonas aeruginosa biofilms. These molecules were found to modulate quorum sensing in reporter strains, and represent some of strongest P. aeruginosa biofilm inhibitors known. Copyright
