56500-03-9Relevant academic research and scientific papers
One-Pot Synthesis of C2 Symmetric and Asymmetric N,N′,N″-Substituted Guanidines from Aryl Isothiocyanates and Amines
Wangngae, Sirilak,Pattarawarapan, Mookda,Phakhodee, Wong
, p. 1121 - 1127 (2016)
Highly substituted guanidines were conveniently prepared through a one-pot reaction between aryl isothiocyanates and amines mediated by the Ph3P-I2/Et3N system. The C 2-symmetric N,N′,N″-substituted guanidines were readily accessed using a 1:2 molar ratio of an aryl isothiocyanate and an amine; while sequential addition of two different amines in equimolar ratios gave rise to asymmetric derivatives. Both primary and secondary amines were found to react preferentially with electron-deficient aryl isothiocyanates, rapidly providing guanidines in good yields under mild conditions.
First iron-catalyzed guanylation of amines: A simple and highly efficient protocol to guanidines
Pottabathula, Srinivas,Royo, Beatriz
supporting information; experimental part, p. 5156 - 5158 (2012/09/22)
The first iron-catalyzed guanylation of amines is reported. Commercially available Fe(OAc)2 acts as an excellent catalyst for the addition of amines to carbodiimides. The reaction is broadly applicable to a variety of primary, secondary, and heterocyclic amines, and tolerates a wide range of functionalities allowing the easy preparation of a large family of guanidines. The low price and low toxicity of the commercially available iron catalyst make this methodology highly attractive.
Influence of Schiff base and lanthanide metals on the synthesis, stability, and reactivity of monoamido lanthanide complexes bearing two Schiff bases
Han, Fubin,Teng, Qiaoqiao,Zhang, Yong,Wang, Yaorong,Shen, Qi
experimental part, p. 2634 - 2643 (2011/06/18)
The monoamido lanthanide complexes stabilized by Schiff base ligand L 2LnN(TMS)2 (L = 3,5-But2-2-(O)- C6H2CH=N-8-C9H6N, Ln = Yb (1), Y (2), Eu (3), Nd (4), and La (5))
