5651-60-5

Basic information

• Product Name: Benzdindeno1,2-bpyran-5,11-dione
• Synonyms: Benzdindeno1,2-bpyran-5,11-dione;indeno[1,2-c]isochromene-5,11-dione
• CAS NO: 5651-60-5
• Molecular Formula: C₁₆H₈O₃
• Molecular Weight: 248.236
• Mol File: 5651-60-5.mol
• Article Data: 11

Chemical Properties

• Melting Point: 258-259 °C
• Boiling Point: 459.4°Cat760mmHg
• Flash Point: 208.6°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 1.26E-08mmHg at 25°C
• Refractive Index: 1.718
• CAS DataBase Reference: Benzdindeno1,2-bpyran-5,11-dione(CAS DataBase Reference)
• NIST Chemistry Reference: Benzdindeno1,2-bpyran-5,11-dione(5651-60-5)
• EPA Substance Registry System: Benzdindeno1,2-bpyran-5,11-dione(5651-60-5)

Safety Data

• Hazardous Substances Data: 5651-60-5(Hazardous Substances Data)

Usage

General Description

Benzdindeno1,2-bpyran-5,11-dione is a chemical compound that belongs to the class of benzodindeno pyran diones. It is a polycyclic aromatic compound with a fused ring structure. Benzdindeno1,2-bpyran-5,11-dione has potential applications in material science, organic synthesis, and pharmaceuticals. It possesses a unique combination of structural and electronic properties, making it valuable for various chemical reactions and processes. In addition, the benzodindeno1,2-bpyran-5,11-dione compound has shown promise in the development of advanced materials and drugs due to its interesting chemical and physical properties.

InChI:InChI=1/C16H8O3/c17-14-10-6-2-3-7-11(10)15-13(14)9-5-1-4-8-12(9)16(18)19-15/h1-8H

Upstream product

• 87-41-2 2-benzofuran-1(3H)-one 
• 16859-59-9 3-hydroxy-1(3H)-isobenzofuranone 
• 89-51-0 Homophthalic acid 
• 119-67-5 o-carboxybenzaldehyde 
• 19147-02-5 2-(2-carboxyphenyl)indan-1,3-dione 
• 15255-42-2 11-acetoxy-6-bromo-6H-dibenzo[a,e]cycloocten-5-one 

Downstream Products

• 81721-78-0 6-propargyl-5H-indeno[1,2-c]isoquinoline-5,11(6H)-dione 
• 81721-81-5 6-(Furan-2-ylmethyl)-5H-indeno[1,2-c]isoquinoline-5,11(6H)-dione 
• 1374209-85-4 N-(3-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)propyl)-4-methylbenzenesulfonamide 
• 1374209-78-5 N-(7-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)heptyl)benzenesulfonamide 
• 1374209-77-4 N-(6-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)hexyl)benzenesulfonamide 
• 1374209-76-3 N-(5-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)pentyl)benzenesulfonamide 
• 1374209-75-2 N-(4-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)butyl)benzenesulfonamide 
• 1374209-74-1 N-(3-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)propyl)benzenesulfonamide 
• 1374209-73-0 N-(2-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)ethyl)benzenesulfonamide 
• 1352142-56-3 6-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)hexyl-4-methylbenzenesulfonate 
• 1352142-55-2 5-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)pentyl-4-methylbenzenesulfonate 
• 1352056-93-9 4-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)butyl-4-methylbenzenesulfonate 
• 1374210-05-5 N-(12-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)dodecyl)-4-bromobenzenesulfonamide 
• 1374210-04-4 N-(11-(5,11-dioxo-5H-indeno[1,2-c]isoquinolin-6(11H)-yl)undecyl)-4-bromobenzenesulfonamide 

Relevant articles and documents

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Indene isoquinoline derivative labeled with stable nitrogen-oxygen free radicals, and preparation method and application

The invention discloses an indene isoquinoline derivative labeled with stable nitrogen-oxygen free radicals, and a preparation method and application thereof in preparation of anti-tumor medicines. The indene isoquinoline derivative has the advantages that the good inhibiting activity is realized on the tumor cell lines, and one part of activity of the compound is equivalent to the activity of theexisting clinical topotecan medicine; the indene isoquinoline derivative can be used for preparing the anti-tumor medicines.

SYNTHESIS AND USE OF DUAL TYROSYL-DNA PHOSPHODIESTERASE I (TDP1)- TOPOISOMERASE I (TOP1) INHIBITORS

The invention described herein pertains to the synthesis and use of certain N-substituted indenoisoquinoline compounds which inhibit the activity Tyrosyl-DNA Phosphodiesterase I (Tdp1) or Topoisomerase I (Top1) or both, or otherwise demonstrate anticancer activity. Also disclosed are novel N-substituted indenoisoquinoline compounds and pharmaceutical compositions comprising the novel N-substituted indenoisoquinoline compounds.