565196-81-8

Basic information

• Product Name: 3H-Pyrazole-3,3,5-tricarboxylic acid, 5-chloro-4,5-dihydro-4-phenyl-, triethyl ester
• CAS NO: 565196-81-8
• Molecular Formula: C18H21ClN2O6
• Molecular Weight: 396.828
• Mol File: 565196-81-8.mol

Chemical Properties

• CAS DataBase Reference: 3H-Pyrazole-3,3,5-tricarboxylic acid, 5-chloro-4,5-dihydro-4-phenyl-, triethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-Pyrazole-3,3,5-tricarboxylic acid, 5-chloro-4,5-dihydro-4-phenyl-, triethyl ester(565196-81-8)
• EPA Substance Registry System: 3H-Pyrazole-3,3,5-tricarboxylic acid, 5-chloro-4,5-dihydro-4-phenyl-, triethyl ester(565196-81-8)

Safety Data

• Hazardous Substances Data: 565196-81-8(Hazardous Substances Data)

Upstream product

• 5292-53-5 diethyl benzalmalonate 
• 340296-21-1 triethyl 4,5-dihydro-4-phenyl-3H-pyrazole-3,5,5-tricarboxylate 

Relevant articles and documents

Reaction of 4,5-dihydro-1H-pyrazole-3,5,5-tricarboxylic acids esters with halogens

Esters of 4-R-4,5-dihydro-1H-pyrazole-3,5,5-tricarboxylic acids with chlorine yield esters of 4-R-5-chloro-4,5-dihydro-3H-pyrazole-3,3,5-tricarboxylic acids that at thermolysis provide the esters of the corresponding 2-chlorocyclopropanetricarboxylic acid. The same esters react with bromine in dichloromethane at room temperature to give a mixture of esters of the corresponding 1H-pyrazole-3,5-dicarboxylic acids and 5-bromo-4,5-dihydro-3,3,5-tricarboxylic acids. From 5,5-diethyl 3-methyl 4,5-dihydro-1H-pyrazole-3,5,5-tricarboxylate and N-iodosuccinimide or a system iodine - silver trifluoroacetate we obtained 1,1-diethyl 2-methyl 2-iodocyclopropane-1,1,2-tricarboxylate.